Tag Archives: Confirmatory Typing

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The Year at a Glance!

Here’s an update at the work we have done this year – thank you so much to all who have supported us, let us strive for greater success in the year 2013! We can do it!



BMDP sets up “Donor Centre” operation

Izrin Al-Edrus, Donor Coordinator

“Please don’t be worried – it’s really just a little inconvenience”, urges Izrin Al-Edrus as he explains to different people from all walks of life how their actions today can actually save someone’s life.

As the donor register expands, more potential matches are being identified from our Singapore database. To support this activity, the BMDP has appointed Izrin to lead a new “Donor Centre” operation. This means that all new donor sign-ups, and those individuals who are identified as a match, have a dedicated Account Manager to work with and answer any specific enquiries they may have; and the usual concern is about what will actually happen during a donor “harvest”.

According to Izrin, “we have more BMDP donors undergoing Verification Typing today than at any other time and this is the credit to the amazing growth we have in the size of the register. Unfortunately, we still have a significant challenge that individuals are often not willing to carry through and make that life-saving donation when the time actually comes”.

The Donor Centre will also implement a buddy system where new donors can meet up and share their experiences with others who have already undergone a bone marrow stem cell harvest. Designed to provide support in overcoming any initial concerns, they can hear first-hand how this life-saving act was a defining moment for each of them and apart from some minor inconvenience; the experience has been a tremendously positive experience in their personal lives.

“It is an amazing experience to be able to find matching donors and to provide them with all the information they need to make that life-saving decision”, concluded Izrin.

From top left: donor's fiancée, Reza's mother, Reza's father, donor, Reza, Reza's brother.

Calling out for a Hero!

From top left: donor's fiancée, Reza's mother, Reza's father, donor, Reza, Reza's brother.
From top left: donor’s fiancée, Reza’s mother, Reza’s father, donor, Reza, Reza’s brother.

The past one week has been amazing! 14 year old transplant recipient, Reza met the 28 year old woman who saved his life for the very first time and the real miracle is a Chinese donor being a perfect match for a young Malay patient!

It’s a “first” for us and it was a real joy to be with them while they both shared their stories amid lots of laughter like real old friends … For our Superwoman (who doesn’t want to be named) she told Reza that she was never worried about making that life-saving donation – she know somebody’s life depended upon her plus it was a safe and simple procedure – but she was very worried it might mean she couldn’t go and watch the first F1 Night Race in Singapore! For football-mad Reza, meeting Superwoman’s fiancé in a matching Arsenal t-shirt really made the match and so a new friendship begins.

Every so often people ask why do I still want to be involved in the BMDP; after all, it is exactly 16 years ago today that Daniel had his transplant and life moves on. Indeed and rarely do we talk about this in a personal context – but every search to find a donor is because another family is struggling through the worst of times and waiting for good news that we have found a potential life-saving match.

So when someone asks you about bone marrow transplants, please share what you know about the BMDP and help us with our mission. We desperately need more donors to sign up – and also you could make a donation to help pay for the tissue typing – with your help, more people will have a chance to survive and meet the hero who saved their life.

Written by Jane

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The doctor is in to address your issues and concerns about being a bone marrow donor

Dr Yvonne Loh

Having signed up as a bone marrow donor, there are still many questions unanswered on what exactly happens when someone is found to be a matching donor for a patient. We asked Dr Yvonne Loh, blood stem cell transplant physician, to give you a simple overview of the most frequent questions our donors ask about being what actually happens during a bone marrow donation.

So what will actually happen if I’m identified as a match?

First of all, we will call you and arrange a time to collect a small blood sample which we will use for “Verification Typing”. This will confirm that you are indeed a suitable match for the patient.

If the doctor selects you as a donor, the next stage is what we call “Donor Workup”. This includes a full physical examination to make sure that you are fit and healthy to donate and during that session the doctor will share more about the donation process including any risks and side effects. You will also be informed if the transplant doctor has requested for either a bone marrow or cells collected from the blood – Peripheral Blood Stem Cell (PBSC) donation. If the transplant doctor has no preference, then you will be able to choose the method you prefer.

Can you explain more about the donation process?

There are two methods of donating bone marrow:

Traditional Bone Marrow Donation is a short procedure done under General Anaesthesia and bone marrow is extracted from the pelvic bone. Usually the donor will be admitted to hospital the evening before and discharged the day after donation when the effects of the anaesthetic have worn off.

Peripheral Blood Stem Cell (PBSC) Donation is an outpatient procedure and the donor is given a small injection of filgrastim – or GCSF – every day for five days. This is a naturally occurring chemical which stimulates production of the bone marrow cells (blood stem cells) which then spill out into the bloodstream where they can be collected through a blood-donation like procedure. The difference is that once the blood is collected, it goes through an aphaeresis machine which removes ONLY the blood stem cells and everything else is returned to the donor. This procedure usually takes 6-7 hours as an outpatient and immediately afterwards the donor is free to leave.




Which is the best method?

Neither method is better than the other although the default for most donor centres today is to harvest blood stem cells using the PBSC method which cuts out the need for a General Anaesthetic. If the donor has a preference, we would try to accommodate that unless the transplant centre specifically makes a request based on the patient’s medical condition.

Are there any side effects?

For the traditional Bone Marrow harvest, there is always some risk associated from a General Anaesthesia but from the actual harvest procedure, serious side effects are very uncommon. As only 5% of the donor’s bone marrow is collected, feedback from our donors usually suggests the after-effect is similar to having a sports “tackle” and they are a little stiff for a couple of days.

With a PBSC harvest, some people experience headaches and / or heaviness to the limbs rather similar to a flu-like ache during the 5 days of hormone injections. This is usually relieved through taking a simple painkiller and in almost all cases, these stop immediately upon collection. Again, serious side effects are very unusual.

What can I expect after I have made the donation?

After a traditional Bone Marrow harvest is completed, most said they would be back at work or studies a day or two after making their donation.

Sometimes a PBSC collection may require two days, but it is an outpatient procedure and the donor does not stay in hospital. After the collection is complete, usually the donor is free to go home or back to work and the bone marrow or blood-forming cells will be back to their normal levels within two to four weeks.

Do I have a choice as to which procedure I prefer?

Sometimes, the transplant doctors will allow you to state a preference and we do try our best to support your preferred method of donation. However, depending on the patient’s condition, the doctor may recommend the procedure that would best aid in the patient’s outcome.

Are there any follow up examinations?

Yes, you will be looked after every step of the way. There will be follow-up sessions scheduled after donation – usually at least one week and one year after your donation. Once the doctor signs off after your last visit, you will not need to return for any subsequent follow-ups. All costs incurred will be covered by the BMDP including any required medicines in the unlikely instance that any treatment is required.


Do I need to incur any costs?

No, you do not need to pay for anything. Any out of pocket expenses will be reimbursed to you including travel expenses as well as any loss of earnings that may result from your donation.

Do you inform my employer that I am a donor?

Yes, we will definitely communicate with any relevant person or individual depending on the donor’s needs. Usually employers are very supportive and willing to support any donors through giving additional leave as necessary to cover the various appointments. We will also talk with other members of the donor’s family if this would be helpful in reassuring them of the procedures involved.